The most direct strategy involves giving bad gifts, cards that actively harm their new controller, such as Steel Golem, which prevents them from casting creature spells, or the notorious Illusions of Grandeur, which causes a 20-life loss when it leaves the battlefield
Etali, Primal Conqueror / Etali, Primal Sickness Speaking of casting free spells, does anybody else think Etali, Primal Conqueror might have been pushed a little too hard
It also brings a nice body, and it's not as bad for aggro as repeatedly gaining life from eg
Yes, it hurts a little, but no pain without gain
However, A dventures in the Forgotten Realms has a cycle of cards that pay homage to the twelve D&D Classes
Its one of the few ways Grixis can deal with enchantments cleanly, and alternating between a Bramblecrush and a Mind Control isnt bad at all