Its a good, uncounterable commander, but it really shines in the 99 for serpent tribal decks, token multipliers like Adrix and Nev, Twincasters, and even as a clone payoff for Sakashima of a Thousand Faces and whatever green pipped partner you run
There are hundreds of viable commanders to run, with strategies ranging from control to midrange to combo, each one shaping the flow and design of your deck
But the advantage of Quandrix/Simic decks is that youre bound to have access to plenty of ramp that will let you either go searching for lands or find ways to earn more mana that isnt necessarily through land sources
And the tinyest of shoutouts to Vibrant Cityscape for adding Yet Another Evolving Wilds to the mix
This is the only confirmed restriction, but others may come down the line
About a week ago I attended an Invitational Qualifier, and there I saw my friend Terrence Gluck playing a R/W/B Devotion deck