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Any effect that specifically sends a permanent to a graveyard also gets around indestructible , since you dont deal lethal damage but simply move the permanent from one zone to another

As mythic rares, these cards are going to be difficult to pack anyway, but these variants are likely to be highly sought after once the set launches, not just for the value a complete set of the elder dragon cards may hold, but also for their eligibility as Commanders

Even if you bin a Think Twice with Alchemy, you are still paying 3 mana for an extra card

With mana ramp, you can accomplish this much earlier

Although not quite it feels about as close to "Destroy a land and your opponent discards a card" as we are likely to see for three mana in these golden situations

Character(s): Elsa, Reck It Ralph, Scar, Kronk