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Functioning much like the adventure half of Callous Sell-Sword, its effect is amplified when targeting Screaming Nemesis

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Smothering Tithe is also a consideration if you want access to more ramp

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And once Ghalta is cheap enough, you can simply drop a 12/12 Trampler into play on turn three or so while everyone else is still trying to ramp with Cultivate

Certain cards (like Manor Guardian, visible in the gallery above) will allow you to seek a card with specific criteria, randomly pulling one from your library that meets that criteria without shuffling afterward something that couldnt happen at the tabletop without a player manually looking through their deck