One of the big ones namely is the rest of the Nine Titans (we're only technically up to three of them if you don't count the Unstable Urza Planeswalker card, with Kristina of the Woods, Daria, Commodore Guff, Bo Levar, and Taysir of Rabiah left) and there are always plenty of characters within the Weatherlight saga even still
Ruin hits all opponents which makes it a must-include if youre trying to make mill happen in Commander
Small changes like these will have a large impact on your games
Next turn you cast Ad Nauseam, draw most of your deck including Reliquary Tower, which you play to keep all the cards
However, its dominance in the 1v1 formats just pushes it over Nadu
But as I played, I noticed that the deck really seems to like having +1/+1 counters on things and it's possible that we could take advantage of it