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Her ability specifically dictates that Doctor abilities trigger twice (and surprise, surprise, all the Doctors have triggered abilities)

Pair this with cards that increase the mana your lands produce

Ping your opponent with a flying infect creature like Viral Drake to get the ball rolling on poison counters so you can then attack with Chained Throatseeker for more infect damage

You can stabilize yourself with some mild lifegain while the Guardian remains impervious to the damage

However, there are better options like Vraska's Contempt which exiles a target creature and gains you 2 life for the same mana cost

Its even better in decks that also use a lot of artifact creatures as it'll meet both requirements