Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Jul 31 - Aug 5
CAS Number: 7481-89-2
InChi: InChI=1S/C27H24O2/c1-27(2)17-16-23(21-6-4-3-5-7-21)24-18-20(12-15-25(24)27)9-8-19-10-13-22(14-11-19)26(28)29/h3-16
16-dihydroxy-5
3-dimethyl-1-oxobutan-2-yl]carbamate
The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583)
Sitravatinib Catalog No.:M14117-2 CAS Number: 7481-89-2Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC50s of 1. 5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0. 5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively. Sitravatinib shows potent single agent antitumor efficacy and enhances the activity of PD 1 blockade through promoting an antitumor immune microenvironment. Product information CAS Number:
US$ 17.95
US$ 16.95
US$ 119.00
US$ 239.50