with an IC50 of 6 nM for human KSP
14b-tetradecahydropicene-4a-carboxylate
Smiles: CC(=O)N(CC1C=CC(F)=CC=1)C1=C(NCC2C=CC=CC=2)C(=O)C2=CC=CC=C2C1=O
) is effective in inhibiting the HT-29 xenograft growth in a nude mouse xenograft model
which also indicates that the inhibition is irreversible in nature
PBOX 6 enamine with an IC50 of 6PBOX 6 is a pyrrolo 1,5 benzoxazepine (PBOX) compound, acts as a microtubule depolymerizing agent and an apoptotic agent. Product information CAS Number: 290814 68 5 Molecular Weight: 396. 44 Formula: C25H20N2O3 Chemical Name: 8 (naphthalen 1 yl) 9 oxa 2 azatricyclo[8. 4. 0. 0,]tetradeca 1(14),3,5,7,10,12 hexaen 7 yl N,N dimethylcarbamate Smiles: CN(C)C(=O)OC1=C(OC2=CC=CC=C2N2C=CC=C21)C1C=CC=C2C=CC=CC2=1 InChiKey: SOIZAFVNIXAZFQ UHFFFAOYSA N InChi: