BACE1-IN-2 255ipexide Smiles: COC1=CC(C=O)=C(Cl)C(Cl)=C1O

Smiles: COC1=CC(C=O)=C(Cl)C(Cl)=C1O

Chemical Name: (cyclopropylmethyl)[(3R

In 90% (72 out of 80) of the cells in which cyclothiazide acts

InChi: InChI=1S/C18H19ClFN7/c1-27-6-4-11(5-7-27)25-18-21-9-15-16(26-18)17(23-10-22-15)24-12-2-3-14(20)13(19)8-12/h2-3

IC50~3-10 µM)

BACE1-IN-2 255ipexide Smiles: COC1=CC(C=O)=C(Cl)C(Cl)=C1OBACE1 IN 2 is a 1,4 Oxazine Secretase 1 (BACE1) inhibitor with an IC50 of 22 nM. Product information CAS Number: 1352416 78 4 Molecular Weight: 421. 35 Formula: C19H15F4N5O2 Chemical Name: N {3 [(2R,3R) 5 amino 3 methyl 2 (trifluoromethyl) 3,6 dihydro 2H 1,4 oxazin 3 yl] 4 fluorophenyl} 5 cyanopyridine 2 carboxamide Smiles: C[C@@]1(N=C(N)CO[C@H]1C(F)(F)F)C1=CC(=CC=C1F)NC(=O)C1=CC=C(C=N1)C#N InChiKey: YCNKUIFVRZSRNL QZTJIDSGSA N InChi: InChI=1S