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Molecular Weight: 340
RepSox is able to successfully replace Sox2 in reprogramming by inhibiting transforming growth factor-β (Tgf-β) signaling
Chemical Name: (4-(4-{[2-(4-chlorophenyl)-4
and high in vivo potency
2014 Sep 1
AG-1517 - CAS# 153436-54-5 Catalog No.:M6400-10 Molecular Weight: 340AG 1517, CAS No. 153436 54 5, is a ATP competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGF receptor stimulation. With human fibroblasts and epidermoid carcinoma cells, PD153035 at nanomolar concentrations rapidly inhibits EGFR autophosphorylation. With breast and ovarian cancer cells,
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