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CAS Number: 1374601-40-7
Molecular Weight: 318
SF-1670 also elevates Akt phosphorylation in murine cells
later studies reveal that SP600125 also suppresses aryl hydrocarbon receptor (AhR)
Mice treated orally with 10 mg CZC24832 per kg body weight twice per day show a substantial decrease of bone and cartilage destruction (53% reduction by histopathological analysis) as well as of overall clinical parameters (38% reduction)
U 0126(ZZ) ogenic acid CAS Number: 1374601-40-7U0126 is a potent and selective non competitive inhibitor of MAP kinase. Inhibits MEK 1 and MEK 2 (IC50 values of 0. 07 and 0. 06 M respectively). Product information CAS Number: 218601 62 8 Molecular Weight: 380. 49 Formula: C18H16N6S2 Synonym: U0126 U 0126 Related CAS Number: 1173097 76 1 (U0126 EtOH) Chemical Name: (2Z, 3Z) 2, 3 bis(amino((2 aminophenyl)thio)methylene)succinonitrile Smiles: NC1=CC=CC=C1S C( N)=C(\C#N) C( C#N)=C(\N) SC1=CC=CC=C1N