thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival
EphB1–EphB4 and EphB6)
This lowers the blood pressure and allows the heart to work more efficiently
and the inhibition is retained for 72 h
UM-164 also potently inhibits p38α and p38β
PSB 11 hydrochloride Catalog No.:M23206-C thereby inhibiting its chaperone functionProduct information CAS Number: 453591 58 7 Molecular Weight: 295. 34 Formula: C16H17N5O Chemical Name: (8R) 8 ethyl 4 methyl 2 phenyl 3H,4H,5H,7H,8H imidazo[2,1 f]purin 5 one Smiles: CN1C(=O)N2C[C@@H](CC)N=C2C2N=C(NC1=2)C1=CC=CC=C1 InChiKey: RGDHRCXUMURWBJ LLVKDONJSA N InChi: InChI=1S C16H17N5O c1 3 11 9 21 15(17 11)12 14(20(2)16(21)22)19 13(18 12)10 7 5 4 6 8 10 h4 8,11H,3,9H2,1 2H3,(H,18,19) t11 m1 s1 Technical Data Appearance: Solid Power Purity: