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120(7):1199-1206
Formula: C27H30F3N3O3
CAS Number: 1253421-94-1
5 μM BMS-345541 treated for 16 h leads to an increase in apoptotic cells in all these cell
CAS Number: 90-47-1
BI-2852 567 120(7):1199-1206BI 2852 is a potent inhibitor of KRAS that binds with nanomolar affinity to a pocket between switch I and II on RAS. BI 2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells. Product information CAS Number: 2375482 51 0 Molecular Weight: 516. 59 Formula: C31H28N6O2 Chemical Name: 5 hydroxy 3 (2 {[({1 [(1 methyl 1H
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