Casopitant mesylate Size:Contact [email protected] for quotation ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16

ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16

It potently reduces global H3K27Me3 mark in cells and demonstrates selectively cell killing effects in cells carrying a heterozygous Y641N mutation

and a t(1/2) of 9

) exhibits half-life (t1/2=9

Formula: C16H16Cl3N

Casopitant mesylate Size:Contact [email protected] for quotation ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of substance P. Casopitant mesylate is also a substrate and a weak to moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy induced nausea and vomiting (CINV) and postoperative nausea and