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mGlu6 and mGlu7 receptors
delays deaths and increases survival rates for mice treated with high doses of cisplatin
4 mg/mL (5
15-dimethoxy-7
and enhances the threshold of pain by activating ATP‐sensitive K+ channel in the brain and spinal cord level
TH588 hydrochloride llow mGlu6 and mGlu7 receptorsTH588 hydrochloride is first in class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1 (IC50= 5 nM). Product information CAS Number: 1640282 30 9 Molecular Weight: 331. 63 Formula: C13H13Cl3N4 Chemical Name: N4 cyclopropyl 6 (2,3 dichlorophenyl)pyrimidine 2,4 diamine; chlorohydrogen Smiles: Cl. NC1N=C(C=C(N=1)C1=CC=CC(Cl)=C1Cl)NC1CC1 InChiKey: FBHMEHNWFXCSKE UHFFFAOYSA N InChi: InChI=1S C13H12Cl2N4. ClH c14 9