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highly potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP) with IC50 of 0
It induces G1 cell cycle arrest and reduces cancer cell clonogenic growth at nanomolar concentrations
and effectively radiosensitizes human glioma cells
Formula: C31H34Cl2N2O3
18)19/h3-7H
Maxacalcitol-D6 Size:Contact [email protected] for quotation highly potent and selective bromodomainMaxacalcitol D6 is the deuterated form of Maxacalcitol (22 Oxacalcitriol), which is a non calcemic vitamin D3 analog and VDR ligand of VDR like receptors. IC50 value: Target: Maxacalcitol (22 Oxacalcitriol)suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Maxacalcitol exhibits similar effects to calcitriol in osteoblast like cells. Maxacalcitol(22 Oxacalcitriol) inhibits tumor growth of osteosarcoma in vitro in combination