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CAS Number: 147591-46-6
Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors
which mediate their binding to acetylated lysine residues on histones and other proteins
75(23):5106-19
BGJ-398 shows a rapid distribution from the vascular compartment into the peripheral tissues
JNK-IN-8 - CAS# 1410880-22-6 60136 CAS Number: 147591-46-6JNK IN 8, also known as JNK Inhibitor XVI, CAS No. 1410880 22 6, is a selective JNK inhibitor that inhibits phosphorylation of c Jun, a direct substrate of JNK, in cells exposed to submicromolar drug in a manner that depends on covalent modification of the conserved cysteine residue. Extensive biochemical, cellular, and pathway based profiling establish the selectivity of JNK IN 8 for JNK and suggests that the compound will be broadly useful as a
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