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CAS Number: 916918-84-8
Zhongguo Yao Li Xue Bao
CAS Number: 1638504-66-1
17)15-8-7-14
2Na/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18
JLK 6 njugates 15 hydrochloride CAS Number: 916918-84-8JLK 6, an isocoumarin, is a selective inhibitor of secretase, with an IC50 value between 10 M 1 mM [1, 2]. The enzyme secretase catalyzes the cleavage of Amyloid precursor protein (APP) to produce Amyloid peptide (A). A is a part of the plaque present in the brain of patients with Alzheimers disease. secretase also targets other substrates like Notch. Notch is a transmembrane protein which is involved in important functions during different stages in
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