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(2011) Nature
Formula: C20H19NO4
Administration of SR9009 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice
There is an 87
Smiles: COC1C(=CC(=CC=1OC)C1=CC(=CN=C1N)C1=CC(O)=CC=C1)OC
PQR-309 - CAS# 1225037-39-7 0216 (2011) NaturePQR 309, CAS No. 1225037 39 7, is an orally bioavailable pan inhibitor of phosphoinositide 3 kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity. PI3K mTOR kinase inhibitor PQR 309 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K mTOR. Activation of
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