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48(11):5199-206
Déciga-Campos M
with IC50 of 47 nM
Chemical Name: 3-((1r
decreased colony formation in methylcellulose/soft agar
Efinaconazole - CAS# 164650-44-6 eprazole 48(11):5199-206Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14 demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14 demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following
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