DRF-1042 Size:10mg solid 786:109-15

786:109-15

2 μM and 1

Smiles: COC1=CN=C(NS(=O)(=O)C2C=CC(N)=CC=2)N=C1

InChi: InChI=1S/C29H28ClN7OS/c1-3-37-27-20(14-24(28(37)38)23-9-4-19(15-25(23)30)26-17-31-18-39-26)16-32-29(34-27)33-21-5-7-22(8-6-21)36-12-10-35(2)11-13-36/h4-9

4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8

DRF-1042 Size:10mg solid 786:109-15DRF 1042 is an orally active derivative of Camptothecin. DRF 1042 acts to inhibit DNA topoisomerase I. DRF 1042 shows good anticancer activity against a panel of human cancer cell lines including multi drug resistance (MDR) phenotype. Product information CAS Number: 200619 13 2 Molecular Weight: 408. 40 Formula: C22H20N2O6 Chemical Name: (19S) 19 ethyl 19 hydroxy 12 (2 hydroxyethoxy) 17 oxa 3, 13 diazapentacyclo[11. 8. 0. 0, . 0, . 0, ]henicosa 1(21),