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MCU i4 is a negative modulator of mitochondrial calcium (Ca2+) uniporter (MCU) complex
Smiles: C#CCOCCOCCOCCOCCOCC(=O)ON1C(=O)CCC1=O
InChiKey: BQAVZGJJQFJSMW-UHFFFAOYSA-N
(R)-2-Hydroxypentanedioic acid
is essential for cell growth and proliferation
KL1333 011381 MCU i4 is a negativeKL1333, a derivative of lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H: quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin induced ototoxicity in mouse cochlear cultures. Product information CAS Number: 1800405 30 4 Molecular Weight: