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G007-LK B-PS Solubility: DMSO: 25 mg/mL

SKU: 89073182288

4.7
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Description

Solubility: DMSO: 25 mg/mL

while the IC50 at the human P2X7 receptor is 0

Zakaria ZA

Epub 2015 Oct 5

Harmine is also a unique regulator of PPARγ expression that acts by inhibiting the Wnt signalling pathway in a cell-specific manner

G007-LK B-PS Solubility: DMSO: 25 mg/mLG007 LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1 2 inhibitor. G007 LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice. G007 LK was first discovered by Dr. Stefan Krauss's team. Product information CAS Number: 1380672 07 0 Molecular Weight: 529. 96 Formula:

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