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also known as MK2452 and AFP-168
to pregnant ewes
controlled clinical trial
InChi: InChI=1S/C13H9Cl2N5
Formula: C38H50N6O5
Icilin - CAS# 36945-98-9 Catalog No.:M10485-2 also known as MK2452 andIcilin is a synthetic super agonist of the transient receptor potential M8 (TRPM8) ion channel. Although structurally not related with menthol it produces an extreme sensation of cold both in humans and animals. It is almost 200 times more potent than menthol and 2. 5 times more efficacious. Despite their similar effects icilin activates the TRPM8 receptor in a different way. Icilin is effective in an experimental model of itch. It is now used as a
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