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Mibefradil 2HCl methyl-N1-(pyridin-2-yl)ethane-1 2-diamine hydrochloride SU5416 selectively inhibits VEGF-driven mitogenesis

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Description

SU5416 selectively inhibits VEGF-driven mitogenesis in a dose-dependent manner with IC50 of 0

Epub 2017 Nov 4

The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK

InChi: InChI=1S/C19H18N4OS/c1-3-24-15-9-7-14(8-10-15)21-19-22-16(12-25-19)18-13(2)20-17-6-4-5-11-23(17)18/h4-12H

1038/s41598-017-08711-6

Mibefradil 2HCl methyl-N1-(pyridin-2-yl)ethane-1 2-diamine hydrochloride SU5416 selectively inhibits VEGF-driven mitogenesisMibefradil 2HCl is calcium channel blocker with moderate selectivity for T type Ca2+ channels displaying Product information CAS Number: 116666 63 8 Molecular Weight: 568. 55 Formula: C29H40Cl2FN3O3 Synonym: Ro 40 5967 dihydrochloride Related CAS Number: 116644 53 2 (free base) Chemical Name: (1S,2S) 2 (2 {[3 (1H 1,3 benzodiazol 2 yl)propyl](methyl)amino}ethyl) 6 fluoro 1 (propan 2 yl) 1,2,3,4 tetrahydronaphthalen 2 yl 2 methoxyacetate dihydrochloride

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