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Macitentan (trade name Opsumit) is an endothelin receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH)
InChi: InChI=1S/C23H23N3O5
Jan Martin Berke
2015 Jan 27
Toxicity of the mitochondrial poison dequalinium chloride in a murine model system
Rosiglitazone hydrochloride - CAS# 302543-62-0 Size:10mg solid Macitentan (trade name Opsumit) isRosiglitazone hydrochloride (BRL 49653 hydrochloride) is a selective, orally active PPAR agonist with EC50s of 30 nM, 100 nM and 60 nM for PPAR1, PPAR2, and PPAR, respectively. Rosiglitazone hydrochloride binds to PPAR with a Kd of approximately 40 nM. Rosiglitazone hydrochloride is also an activator of TRPC5 (EC50=~30 M) and an inhibitor of TRPM3. Product information CAS Number: 302543 62 0 Molecular Weight: 393. 89 Formula: C18H20ClN3O3S Synonym:
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