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5’-[(Desloratadine)methyl] Rupatadine-d8 Catalog No.:M26414-C 1 nM for TXA2 receptor

SKU: 87010801834

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Description

1 nM for TXA2 receptor antagonism BM 567 is acting as an inhibitor of thromboxane A2 (TXA2) synthase and an antagonist of the TP receptor

It allosterically binds (Kd 10-30 nmol/L) to the regulatory Zn(2+) binding domain of HDAC4 that locks the protein in a conformation preventing HDAC4/N-CoR/HDAC3 complex formation

Smiles: CN1C=C(C=N1)C1C=CC(=CC=1)S(=O)(=O)N1C=C(/C=C/C(=O)NC2=CC=CC=C2N)C=C1

Vasicinone is a quinazoline alkaloid isolated from the Adhatoda vasica plant

Linderalactone also inhibits the proliferation of the lung cancer A-549 cells with an IC50 of 15 µM

5’-[(Desloratadine)methyl] Rupatadine-d8 Catalog No.:M26414-C 1 nM for TXA2 receptorProduct information CAS Number: 1794669 33 2 Molecular Weight: 732. 81 Formula: C45H43Cl2N5 Chemical Name: 13 chloro 2 [1 ({5 [(4 {13 chloro 4 azatricyclo[9. 4. 0. 0,]pentadeca 1(15),3,5,7,11,13 hexaen 2 ylidene}(2,2,6,6 H)piperidin 1 yl)methyl]pyridin 3 yl}methyl)(2,2,6,6 H)piperidin 4 ylidene] 4 azatricyclo[9. 4. 0. 0,]pentadeca 1(15),3,5,7,11,13 hexaene Smiles:

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