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[Epub ahead of print] PubMed PMID: 25611025
and significantly ehhances the inhibition via 10
Formula: C22H33N3O4
Theodoulou NH
and genetic approaches
SF-1670 - CAS# 345630-40-2 66054 [Epub ahead of print] PubMedSF 1670, CAS No. 345630 40 2, is a specific phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor. SF 1670 specifically binds to the active site of PTEN inhibiting its activity with an IC50 value of 2 M. The innate immune responses can be enhanced and the severity of neutropenia related infection can be alleviated by augmenting phosphatidylinositol (3, 4, 5) trisphosphate in transfused neutrophils with PTEN inhibitor SF 1670,
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