Baccatin III 19346 Indirubin Derivative E804 also inhibits

Indirubin Derivative E804 also inhibits CDK2/CycE with an EC50 of 0

InChi: InChI=1S/C21H19FN8O2/c1-23-15-10-17(26-13-5-4-8-29(21(13)32)18-6-2-3-7-24-18)28-30-16(11-25-19(15)30)20(31)27-14-9-12(14)22/h2-8

Barrientos JC

1021/ml200199c

from a weak inhibition of cell proliferation in human erythroleukaemia cell line (K562) to a strong inhibition in human neuroblastoma cells (SK-N-AS)

Baccatin III 19346 Indirubin Derivative E804 also inhibitsBaccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs. Product information CAS Number: 27548 93 2 Molecular Weight: 586. 63 Formula: C31H38O11 Chemical Name: (1S,2S,3R,4S,7R,9S,10S,12R,15S) 4,12 bis(acetyloxy) 1,9,15 trihydroxy 10,14,17,17 tetramethyl 11 oxo 6 oxatetracyclo[11. 3. 1. 0,. 0,]heptadec 13 en 2 yl