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A-485 induces a comparable decrease in H3K27Ac in all five prostate cancer cell lines
Solubility: DMSO: 21 mg/mL(45
with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5
Smiles: CC(=O)N1CCN(CC1)C1=CC(OC)=C(C=C1)NC1=NC(NC2=CC(=CC=C2)NC(=O)C=C)=C(C=N1)C(F)(F)F
PubMed PMID: 31189530
1A-116 16454 A-485 induces a comparable decrease1A 116 is a Rac1 inhibitor, with antitumoral and antimetastatic effects in several types of cancer, such as breast cancer. 1A 116 prevents Rac1 regulated processes involved in the primary tumorigenesis and metastastic processes . Product information CAS Number: 1430208 73 3 Molecular Weight: 307. 31 Formula: C16H16F3N3 Chemical Name: N' (3,5 dimethylphenyl) N [2 (trifluoromethyl)phenyl]guanidine Smiles: CC1=CC(=CC(C)=C1)NC(=N)NC1=CC=CC=C1C(F)(F)F