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654671-78-0 (Sitagliptin Phosphate)
Top HIV Med
Filippo Spriano
21(8-9):1104-9
6-²H₅)phenyl]propyl]amino}propanoyl]pyrrolidine-2-carboxylate
CX-5461 dihydrochloride Catalog No.:M14526-2 654671-78-0 (Sitagliptin Phosphate)CX 5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I mediated rRNA synthesis, with IC50s of 142 nM in HCT 116, 113 nM in A375, and 54 nM in MIA PaCa 2 cells, and shows little or no effect on Pol II (IC50 25 M). Product information Molecular Weight: 586. 54 Formula: C27H29Cl2N7O2S Chemical Name: 4 (4 methyl 1,4 diazepan 1 yl) N [(5 methylpyrazin 2 yl)methyl] 8 oxo 11 thia 1,3 diazatetracyclo[8. 7. 0. 0,. 0,]heptadeca
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