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FD-IN-1 eceptor antagonists-2 Chemical Name: 9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acid

SKU: 82914124320

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Description

Chemical Name: 9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acid

CAS Number: 65281-77-8

Tomatine is a glycoalkaloid

InChi: InChI=1S/C20H13N3O/c24-20-17-12(9-21-20)15-10-5-1-3-7-13(10)22-18(15)19-16(17)11-6-2-4-8-14(11)23-19/h1-8

Smiles: COC1C=CC=C(OC)C=1C1C=CC(C[C@H](NC(=O)C2C(Cl)=CC=CC=2Cl)C(O)=O)=CC=1

FD-IN-1 eceptor antagonists-2 Chemical Name: 9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acidFD IN 1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD IN 1 also inhibits factor XIa (FXIa) and Tryptase 2 with IC50s of 7. 7 and 6. 5 M, respectively. Product information CAS Number: 1646682 14 5 Molecular Weight: 377. 43 Formula: C23H23NO4 Chemical Name:

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