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InChi: InChI=1S/C41H72N2O6/c1-35(2
and with reduced inhibitory activity against PI3Kβ
InChiKey: YRRKLBAKDXSTNC-WEVVVXLNSA-N
Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von Hippel-Lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinities
added 30 min prior to Carbachol treatment 48 h) fully abolishes carbachols timulated cell proliferation
W-7 hydrochloride Catalog No.:M18510-C InChi: InChI=1S/C41H72N2O6/c1-35(2W 7 hydrochloride is a selective calmodulin antagonist. W 7 hydrochloride inhibits the Ca2+ calmodulin dependent phosphodiesterase and myosin light chain kinase with IC50 values of 28 M and 51 M, respectively. W 7 hydrochloride induces apoptosis and has antitumor activity. Product information CAS Number: 61714 27 0 Molecular Weight: 377. 33 Formula: C16H22Cl2N2O2S Chemical Name: N (6 aminohexyl) 5 chloronaphthalene 1 sulfonamide hydrochloride Smiles:
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