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98 μM) in cellular NanoBRET assay
E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide
1-10 µM final concentration in various in vitro assays
InChi: InChI=1S/C13H18Cl2N2O3
suggesting its therapeutic potential
Neuronal-LSB3i size:1000X; 0.5ml+0.5ml 98 μM) in cellular NanoBRETPNU 282987 is a potent agonist of 7 containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor. PNU 282987 has negligible activity against 11 and 34 nAChRs as well as a panel of monoamine, muscarinic, glutamate, and GABA receptors, except 5 HT3 with Ki of 930 nM. Product information Chemical Name: Neuronal LSB3i Technical Data Appearance: Solid Power. Purity: 98% (or refer to the Certificate of Analysis)
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