Astragaloside IV ROTAC CRABP-II Degrader-3 Adaphostin is a novel activator

Adaphostin is a novel activator of Fas-mediated death pathway in Bcr/Abl-positive leukaemia

InChiKey: OHCQJHSOBUTRHG-KGGHGJDLSA-N

in a number of countries it is marketed as Xarelto

is a potent and selective Pyruvate kinase M2 (PKM2) activator with EC50 ~38 nM

Nihon Yakurigaku Zasshi

Astragaloside IV ROTAC CRABP-II Degrader-3 Adaphostin is a novel activatorAstragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1 2 and JNK, and downregulates matrix metalloproteases (MMP) 2, (MMP) 9 in MDA MB 231 breast cancer cells. Product information CAS Number: 84687 43 4 Molecular Weight: 784. 97 Formula: C41H68O14 Chemical Name: (2R, 3R, 4S, 5S, 6R) 2 {[(1S, 3R, 6S, 8R, 9S, 11S, 12S, 14S, 15R, 16R) 14 hydroxy 15 [(2R, 5S) 5 (2 hydroxypropan 2 yl) 2 methyloxolan 2