CHIR99021 HCl - CAS# 1797989-42-4 THP 3-dihydro-1H-isoindol-4-yl]oxy}acetamide hydrochloride

3-dihydro-1H-isoindol-4-yl]oxy}acetamide hydrochloride

and evaluation of highly potent FAK-targeting PROTACs

CAS Number: 594839-88-0

1594094-64-0

As found with previous NSAIDs

CHIR99021 HCl - CAS# 1797989-42-4 THP 3-dihydro-1H-isoindol-4-yl]oxy}acetamide hydrochlorideCHIR99021 HCl, CAS No. 1797989 42 4, also known as CT99021, is a glycogen synthase kinase 3 (GSK3) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR99021 inhibits GSK 3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 for proliferation is about 10M. Product information CAS Number: 1797989 42 4 Molecular Weight: 501. 80 Formula: C22H19Cl3N8 Synonym: CT 99021 Related CAS Number: 252917 06 9 (free base)