AKT-IN-VIII - CAS# 612847-09-3 size:Contact [email protected] for quotation 3-d]pyrimidin-7-one 2-hydroxypropane-1

3-d]pyrimidin-7-one 2-hydroxypropane-1

Chemical Name: (S)-(4-fluorophenyl)(3-(3-(4-fluorophenyl)-1

in liver microsomes of rats

Direct activation of the apoptosis machinery as a mechanism to target cancer cells

Teymouri M

AKT-IN-VIII - CAS# 612847-09-3 size:Contact [email protected] for quotation 3-d]pyrimidin-7-one 2-hydroxypropane-1AKT IN VIII, CAS No. 612847 09 3, also known as AKTi 1 2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKI activity and aryl hydrocarbon receptor pathway. AKT IN VIII suppresses hyperthermia induced Ndrg2 phosphorylation in gastric cancer cells. AKT IN VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium