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11-bis[(4-methoxyphenyl)methyl]-3
InChiKey: NUKYPUAOHBNCPY-UHFFFAOYSA-N
including human T-cell acute lymphoblastic leukaemia (T-ALL)
The synaptic density is reduced by Piericidin A treatment in P301S+/+ mice
Ducharme M
bpV(phen) trihydrate 310 11-bis[(4-methoxyphenyl)methyl]-3bpV(phen) trihydrate, a insulin mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP and PTP 1B, respectively. bpV(phen) trihydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) trihydrate strongly induces the secretion of a large number of chemokines and pro inflammatory cytokines, and it activates a Th1 type pathway (IL 12, IFN).
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