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Bohemine (0-30 µM
10 mg/kg=33 days
65(5):435-44
Loganin is a naturally occuring iridoid glycoside with antioxidant hepatoprotective and neuroprotective effects as well as a COX-1 inhbitor with IC50 value of 355 M suppressing the formation of TNF- and diminishing the production of nitric oxide
Functionalized cereblon ligand for PROTAC® research and development
Capmatinib HCl hydrate - CAS# 1865733-40-9 Laurdan Bohemine (0-30 µMCapmatinib HCl hydrate, CAS No. 1865733 40 9, also known as INCB28060 and INC280, is an orally bioavailable inhibitor of the proto oncogene c Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c Met inhibitor INC280 selectively binds to c Met, thereby inhibiting c Met phosphorylation and disrupting c Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c Met protein or
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