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PF-04634817 Catalog No.:M21127-C Smiles: C[C@H]1COC2(CCN(CC2)C2=NC(=O)C3=CC(=CC(=C3S2)[N+]([O-])=O)C(F)(F)F)O1

SKU: 76653461889

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Description

Smiles: C[C@H]1COC2(CCN(CC2)C2=NC(=O)C3=CC(=CC(=C3S2)[N+]([O-])=O)C(F)(F)F)O1

Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(N[C@H]2CN(CCCCCCCNC(=O)COC3=CC=CC4C(=O)N(C5CCC(=O)NC5=O)C(=O)C=43)CCC2)=NC=C1Cl

3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S

Chemical Name: 2-{2-fluoro-[1

interleukin-6 (IL-6)

PF-04634817 Catalog No.:M21127-C Smiles: C[C@H]1COC2(CCN(CC2)C2=NC(=O)C3=CC(=CC(=C3S2)[N+]([O-])=O)C(F)(F)F)O1PF 0463481 is a potent and orally active dual CCR2 CCR5 antagonist with comparable human and rodent CCR2 potency (rat IC50=20. 8 nM), and displays 10 20 fold less rodent CCR5 potency (rat IC50=470 nM). PF 0463481 is safe and well tolerated and has the potential for the study of diabetic nephropathy. Product information CAS Number: 1228111 63 4 Molecular Weight: 511. 58 Formula: C25H36F3N5O3 Chemical Name: (3S,4S) 3 methoxy N [(1R,3S) 3 (propan 2 yl) 3

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