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84(2):110-5
CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1
InChiKey: NDFKBGWLUHKMFY-UHFFFAOYSA-N
Solubility: DMSO up to 15 mM
Iremashvili VV
Neratinib (HKI-272) vinostat) 84(2):110-5Neratinib, also known as HKI 272 or PB272, is an orally available, irreversible inhibitor of the HER 2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER 2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP binding pocket of the receptor. Product information CAS Number: 698387 09 6 Molecular Weight: 557. 04 Formula: C30H29ClN6O3 Synonym:
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