Pay in 4 interest-free payments of $21.25 Learn more
Ships within 48 hours · Estimated delivery Aug 17 - Aug 22
J Lipid Res
23(3):427-40
InChi: InChI=1S/C19H21N3O/c1-21-9-6-15(7-10-21)18-17-5-3-2-4-14(17)8-11-22-16(13-23)12-20-19(18)22/h2-5
CID53347902
Formula: C25H23IN6O
Ro 48-8071 viol J Lipid ResRo 48 8071 is an orally active cholesterol synthesis inhibitor or a 2,3 oxidosqualene: lanosterol cyclase (OSC) inhibitor. OSC (EC 5. 4. 99. 7) represents a unique target for a cholesterol lowering drug. Partial inhibition of OSC should reduce synthesis of lanosterol and subsequent sterols, and also stimulate the production of epoxysterols that repress HMG CoA reductase expression, generating a synergistic, self limited negative regulatory loop.
US$ 4558.51
US$ 40.00
US$ 60.00
US$ 1449.50
US$ 337.50
US$ 52.00