(3R, 5R)-Rosuvastatin Lactone 797 dihydrochloride 24-72 h) shows anti-proliferative activity

24-72 h) shows anti-proliferative activity in U-937 cells

80-90% of the dose is excreted in urine as unchanged drug and metabolites

1S)-2-hydroxy-1-phenyl-N-[4-(pyridin-4-yl)phenyl]ethane-1-carbamimidic acid

Smiles: CC1(C)[C@H](CCC(N)=O)C2C(C)=C3N4[C@H]5[C@H](CC(N)=O)[C@@]3(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@@H]3[C@@H](CO)O[C@@H]([C@@H]3O)N3C=[N+](C6=CC(C)=C(C)C=C36)[Co-3]364(C)[N+]4C(=C(C)C7[C@@H](CCC(N)=O)[C@](C)(CC(N)=O)[C@@]5(C)[N+]3=7)[C@@](C)(CC(N)=O)[C@H](CCC(N)=O)C=4C=C1[N+]6=2

Smiles: C[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O

(3R, 5R)-Rosuvastatin Lactone 797 dihydrochloride 24-72 h) shows anti-proliferative activity(3R,5R) Rosuvastatin Lactone is an isomer of Rosuvastatin Lactone. Product information CAS Number: 1422954 11 7 Molecular Weight: 463. 52 Formula: C22H26FN3O5S Chemical Name: N [4 (4 fluorophenyl) 5 [(E) 2 [(2R,4R) 4 hydroxy 6 oxooxan 2 yl]ethenyl] 6 (propan 2 yl)pyrimidin 2 yl] N methylmethanesulfonamide Smiles: CC(C)C1=NC(=NC(=C1 C=C [C@H]1C[C@@H](O)CC(=O)O1)C1=CC=C(F)C=C1)N(C)S(C)(=O)=O InChiKey: SOEGVMSNJOCVHT ZUQFGZKASA N InChi: InChI=1S