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Chemical Name: 1-(2 (Diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride
55)41(53)58-7
InChiKey: ITTRLTNMFYIYPA-UHFFFAOYSA-N
InChi: InChI=1S/C25H27N5/c1-3-9-22-19(7-1)12-13-20-8-2-4-10-23(20)25(22)21-14-17-30(18-15-21)16-6-5-11-24-26-28-29-27-24/h1-4
which correlates with effects on tumor growth
BSJ-03-123 rescein Diacetate Chemical Name: 1-(2 (Diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochlorideBSJ 03 123 is a Selective Cdk6 degrader. BSJ 03 123 exploits protein interface determinants to achieve proteome wide selectivity for the degradation of cyclin dependent kinase 6 (CDK6). Pharmacologic CDK6 degradation targets a selective dependency of acute myeloid leukemia cells, and transcriptomics and phosphoproteomics profiling of acute degradation of CDK6 enabled dynamic mapping of its immediate role in coordinating signaling and transcription.