Nelonicline does bind to α3β4* nAChRs in human IMR-32 neuroblastoma cells (Ki=60 nM)
InChiKey: PZUJQWHTIRWCID-HXUWFJFHSA-N
InChi: InChI=1S/C35H49N3O4/c1-21(2)10-9-11-22(3)28-14-15-29-27-20-31(26-18-25(39)19-32(40)23(26)4)38-34(42)36(24-12-7-6-8-13-24)33(41)37(38)30(27)16-17-35(28
the increase excretion of 90Sr was obvious and no side effects was observed among them
InChiKey: OTGPYEHFRKGRIZ-UHFFFAOYSA-N
BMS-066 hydroxypyridine-2-carboxylate Nelonicline does bind to α3β4*BMS 066 is an IKK Tyk2 pseudokinase inhibitor, with IC50s of 9 nM and 72 nM, respectively. Product information CAS Number: 914946 88 6 Molecular Weight: 379. 42 Formula: C19H21N7O2 Chemical Name: 2 methoxy N ({6 [3 methyl 7 (methylamino) 3,5,8,10 tetraazatricyclo[7. 3. 0. 0,]dodeca 1,4,6,8,11 pentaen 11 yl]pyridin 2 yl}methyl)acetamide Smiles: CNC1N=C2NC(=CC2=C2C=1N=CN2C)C1=CC=CC(CNC(=O)COC)=N1 InChiKey: ULTCRVJUAZCGPP UHFFFAOYSA N InChi: InChI=1S