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OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells
Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1)C(=O)NCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21
Stepharine has also shown to inhibit cholinesterase in vitro
) blocks the androgen-axis and inhibits androgen-dependent tumor growth
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms
Isocorydine de-O-C5-NH2 hydrochloride OSI-420 (CP-473420) is an activeIsocorydine is isolated from Dicranostigma leptopodum (Maxim.) Fedde (DLF). Isocorydine combines with Doxorubicin (DOX) has a promising potential to eradicate hepatocellular carcinoma (HCC). Product information CAS Number: 475 67 2 Molecular Weight: 341. 40 Formula: C20H23NO4 Chemical Name: (9S) 4,15,16 trimethoxy 10 methyl 10 azatetracyclo[7. 7. 1. 0,. 0,]heptadeca 1(16),2,4,6,13(17),14 hexaen 3 ol Smiles: