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PMID: 33017361
PubMed PMID: 27165263
a human metabolite of naloxone
X-linked inhibitor of apoptosis protein (X-IAP)
and LAG3 on tumor infiltrating lymphocytes and circulating T cells
BMS-688521 phenyl Salicylic Acid PMID: 33017361BMS 688521 is a highly potent, orally active inhibitor of the LFA 1 ICAM interaction, with an IC50 of 2. 5 nM in the adhesion assay and an IC50 of 60 nM in the MLR assay. BMS 688521 is efficacious in a mouse allergic eosinophilic lung inflammation model. Product information CAS Number: 893397 44 9 Molecular Weight: 536. 37 Formula: C26H19Cl2N5O4 Chemical Name: 6 [(5S,9R) 9 (4 cyanophenyl) 3 (3,5 dichlorophenyl) 1 methyl 2,4 dioxo 1,3,7 triazaspiro[4.