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2-Methylcitric acid l-1-yl)methyl]benzoic acid-d3 AZD5582 results in cIAP1 degradation

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Description

AZD5582 results in cIAP1 degradation and caspase-3 cleavage within tumor cells and causes substantial tumor regressions following two weekly doses of 3

GNA002 can specifically and covalently bind to Cys668 within the EZH2-SET domain

1984 Apr 18

Thalidomide D4 is a deuterium labeled Thalidomide

Molecular Weight: 2041

2-Methylcitric acid l-1-yl)methyl]benzoic acid-d3 AZD5582 results in cIAP1 degradation2 Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2 methylcitric acid cycle. 2 Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2 Methylcitric acid markedly inhibits ADP stimulated and uncoupled respiration in mitochondria supported by glutamate. Product information CAS Number: 6061 96 7 Molecular Weight: 206. 15 Formula: C7H10O7 Chemical Name: 2 hydroxy 1 methylpropane

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