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4-methyl Erlotinib 14591 Vacuolin-1 inhibits autophagy by impairing

SKU: 65476287927

4.2
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Description

Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition

Escherichia

CAS Number: 153252-36-9

CAS Number: 1103500-20-4

CAS Number: 2426616-55-7

4-methyl Erlotinib 14591 Vacuolin-1 inhibits autophagy by impairing4 methyl Erlotinib is an analog of erlotinib by the addition of a methyl group at the four position of the phenyl group. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR) . The epidermal growth factor receptor (EGFR) autocrine pathway has been important for cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread . Erlotinib inhibits EGFR

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