EGFR mutant-IN-1 Catalog No.:M17489-C twice daily) causes an inhibition

twice daily) causes an inhibition of tumor growth in NCr athymic mice bearing established SW620 human colorectal cancer xenografts

and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines

SQ109 showed activity against both drug susceptible and Multi-drug-resistant tuberculosis bacteria

The genotoxicity of Verminoside on human lymphocytes is associated with elevated levels of PARP-1 and p53 proteins

with aclculated Ki of 0

EGFR mutant-IN-1 Catalog No.:M17489-C twice daily) causes an inhibitionEGFR mutant IN 1, a 5 methylpyrimidopyridone derivative, is a potent and selective EGFRL858R T790M C797S mutant inhibitor with an IC50 of 27. 5 nM, while being a significantly less potent for EGFRWT (IC50 >1. 0 M). Product information Molecular Weight: 632. 17 Formula: C34H39ClFN7O2 Chemical Name: (R) 6 (2 chloro 3 fluorophenyl) 5 methyl 2 ((3 methyl 4 (4 methylpiperazin 1 yl)phenyl)amino) 8 (1 propionylpiperidin 3 yl)pyrido[2, 3 d]pyrimidin 7(8H) one